What is Peyronie’s disease commercial?

What is Peyronie’s disease commercial?

The ad encourages them to seek treatment if they believe they may have the condition, in which a buildup of fibrous scar tissue causes an erectile curvature of the penis. The commercial is Endo’s first to promote the use of Xiaflex for Peyronie’s disease.

How do you get Peyronie’s disease?

Peyronie’s disease is likely caused by minor injury to the penis. (See penile trauma.) This type of damage is most often caused by vigorous sex (such as bending the penis during penetration or pressure from a partner’s pubic bone), though it can also be caused by sports or other accidents.

What is Xiaflex used to treat?

This medication is used to treat certain conditions (Dupuytren’s contracture, Peyronie’s disease) that are caused by a certain protein (collagen) in your body. Collagen is a tough and strong substance and is found in the knots/cords of the hand in Dupuytren’s contracture or plaques in the penis in Peyronie’s disease.

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Does Xiaflex work for Peyronie’s disease?

XIAFLEX ® (collagenase clostridium histolyticum) is the only nonsurgical treatment option for appropriate adult men with Peyronie’s disease approved by the Food and Drug Administration (FDA). Treatment involves a series of injections given by trained urologists in their office.

What causes bent carrot disease?

Flaccid and erect penis

The cause of Peyronie’s disease isn’t completely understood, but a number of factors appear to be involved. It’s thought Peyronie’s disease generally results from repeated injury to the penis. For example, the penis might be damaged during sex, athletic activity or as the result of an accident.

What causes bent carrot?

Prescription medication Xiaflex’s first-ever TV ad, titled “Bent Carrot,” recently prompted some awareness of Peyronie’s Disease, a condition stemming from repeated injuries that leads to a significantly bent or curved penis. The spot sees a man and woman in a kitchen, standing before a stack of carrots.

Can peyronies be reversed?

Treatment for Peyronie’s disease. There’s no cure for Peyronie’s disease, but it’s treatable and may go away on its own. Though it may be tempting to request medication right away, many doctors prefer the “watchful waiting” approach if your symptoms aren’t severe.

Can I fix Peyronie’s disease myself?

PD can often self-correct or be treated with injections that dissolve scar tissue from the penis. Surgical removal of the scar tissue or correction with penile implant surgery may also be used.

What happens if Peyronie’s disease is left untreated?

If left untreated, Peyronie’s disease may cause fibrotic, nonexpansile thickening of relatively discrete areas of the corpora tunica, typically resulting in focal bend, pain or other functional or structural abnormalities of the erect penis. Many cases resolve without treatment.

Why was xiaflex discontinued?


This is the result of a business decision made by Actelion Pharmaceuticals Pty Ltd, a Janssen Pharmaceutical Company of Johnson & Johnson, and not the result of safety or efficacy considerations of XIAFLEX®.

Are xiaflex injections painful?

Pain. Although Xiaflex is not uncomfortable to receive, some patients have significant pain for up to 48 hours after the injection, with rare patients having discomfort beyond this period.

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How much do xiaflex injections cost?

Xiaflex costs $3,300 an injection, so a full course of eight injections would cost about $26,000, in addition to a doctor’s fee. Doctors already use less expensive drugs off-label to treat Peyronies, including injections of a generic blood pressure drug.

What is the success rate of xiaflex?

Xiaflex Success Rates

Success rates vary but studies demonstrate an average 34% improvement in the curvature (or 17-degree decrease from baseline curvature). 60% of men getting Xiaflex experienced improvement compared to 30% with placebo.

What is the success rate of Xiaflex for Peyronie’s disease?

Studies have shown 34% improvement in penile curvature in men who underwent treatment with Xiaflex injection compared to 18% improvement in men treated with saline injection.

Is Peyronie’s permanent?

Peyronie’s disease is usually a permanent condition. True Peyronie’s disease rarely goes away on its own, but can occasionally change even years after diagnosis in response to further injuries. The changes in the penis can always be improved using a variety of treatments.

Does mild Peyronie’s go away?

Peyronie disease often happens in a mild form that heals on its own in 6 to 15 months. There is no cure for Peyronie disease.

Is Peyronie’s disease serious?

Although Peyronie’s disease is serious, it is not fatal. Many studies point to the condition as being a contributing factor in the development of depression and anxiety in affected men.

How do you get rid of curvature?

How much curve is normal?

As a rule of thumb, a curved penis typically does not need medical intervention and you don’t need to worry about it if (Brant, 2018): It isn’t greater than a 30° curve. It doesn’t cause any pain (especially during sex).

How long can the average man stay erect?

Is it normal to have an erection for two hours? Erections typically last a few minutes or, in some cases, up to about a half hour. If you have an erection that lasts more than a four hours (priapism) or one that’s unrelated to sex, talk to your doctor right away or seek emergency care.

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Can I live with Peyronie’s disease?

Peyronie’s disease doesn’t need to affect most areas of your life. In general, problems associated with Peyronie’s are restricted to the bedroom. However, if your Peyronie’s disease needs treatment, it’s important to think about how you are going to deal with aftercare in advance.

Is XIAFLEX available?

This medicine is available only through a restricted program called Xiaflex® REMS Program. Doctors who are enrolled in the restricted program can write a prescription for this medicine.

Does insurance cover XIAFLEX?

Xiaflex is covered by all major US health insurance plans.

Precertification is necessary and typically takes 1-2 weeks. All associated costs including doctor visits are typically covered by health plans.

Is there a generic for XIAFLEX?

Xiaflex is available in a generic form as collagenase Clostridium histolyticum.

Where is Xiaflex injected?

Xiaflex is designed to be injected into the collagen scar tissue in the penis and dissolve it. The medication is FDA-approved for men with stable curvature between 30 and 90 degrees, and is not approved for men with complex deformities, calcified scar, or scar on the underside of the penis.

How long does it take Xiaflex to work?

Treatment cycles are typically spaced about 4-6 weeks apart. Some men may see improvements after one or two cycles, while men with severe curvatures may benefit more from three or four cycles.

Can I buy Xiaflex online?

Buy Xiaflex (collagenase clostridium hist) Online | Blink Health. Enjoy $5 OFF your first order, automatically applied at checkout!

How do I order Xiaflex?

The Specialty Pharmacy Provider (SPP) will fill a patient-specific prescription for XIAFLEX ®, bill the patient’s insurance for the product, and then ship it.

How do I get Xiaflex?

How much you pay for XIAFLEX depends on your health benefits or insurance coverage. To find out if you qualify, call 1-800-743-2382.

Is Xiaflex permanent?

Serious injury to the penis, including penile fracture (corporal rupture), has been reported in patients receiving Clostridium histolyticum injection (Xiaflex) for treatment of Peyronie’s disease. Surgery may be required to treat the injury, but in some cases the damage may be permanent.

What is the newest treatment for Peyronie’s disease?

Eur J Rheumatol Inflamm.

How long does Peyronie’s disease take to develop?

Peyronie’s disease is a wound healing disorder, the injury or trauma that initiates it often being subclinical, and the symptoms usually develop and change over some 6–12 months before the chronic phase ensues.

Does viagra keep you hard after coming?

Strictly speaking, no, Viagra does not keep you hard after ejaculation. Nevertheless, studies suggest that it could reduce your refractory period, and it will work for 4-6 hours, meaning that once your refractory period’s over, you should have no trouble getting another erection.

Is xiaflex FDA approved?

In December 2013, collagenase clostridium histolyticum for injection (Xiaflex; Auxilium Pharmaceuticals) became the first pharmacologic treatment to receive US Food and Drug Administration (FDA) approval for the treatment of Peyronie’s disease in men with a palpable plaque and curvature deformity of at least 30 degrees …

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